Cellular senescence is a state where cells permanently stop dividing but remain metabolically active, often in response to stress or damage. Senescent cells are known to play a key role in wound ...
Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular ...
Hair loss and graying, the earliest visible hallmarks of skin aging, result from the functional decline of hair follicle stem ...
Moreover, some tumor suppressor pathways lead to aging in line with the theory of antagonist pleiotropy. According to the evolutionary-selected disposable soma theory, aging should affect primarily ...
There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...
In a recent study published in the journal Science Advances, a large team of researchers in the United States examined the detrimental effects of ketogenic diets. The study used murine models and ...
T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...
The field of immunology of ageing is rapidly evolving, with T cells playing a pivotal role in maintaining immune competence and overall organismal ...
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