Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposium on Gain of Function (GOF) research. Convened in December 2014 by the National Research Council ...
The p53 tumor suppressor gene is a transcription factor (TF) mutated in over half of all human cancers. The majority of p53 mutations are missense mutations incurred within the DNA binding domain.
Recently, there has been extensive debate about the benefits and risks of dual use research of concern (DURC), particularly with the use of gain-of-function (GOF) experiments in potentially pandemic ...
The Covid-19 pandemic has brought the Gain of Function (GoF) research back into the limelight. But what does GoF research means? And what does it has to do with the advent of the Covid-19 virus? GoF ...
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COVID-19 has now infected nearly 120,000 people, killing more than 4,600 in the process in a devastating outbreak which has now been declared a pandemic. Italy has been placed on lockdown as the ...
The National Institutes of Health (NIH) plans to continue creating novel pandemic viruses in apparent defiance of an executive order signed by President Donald Trump calling for a crackdown on the ...
AMR in India – can Gain-of-Function (GoF) research prevent the next pandemic? Now, as far as Covid-19 is concerned, the WHO has still not made its stance clear whether the virus was a result of a GoF ...
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